Balkan Journal of Medical Genetics

ALPHOID DNA VARIATIONS AND NON-DISJUNCTION IN DOWN’S SYNDROME: FLUORESCENCE IN SITU HYBRIDIZATION AND CYTOGENETIC STUDIES
Vorsanova SG1,*, Yurov YB2, Beresheva AK1, Iourov IY2, Monakhov VV2, Sharonin VO1, Demidova IA2, Kravets VS1
*Corresponding Author: Professor Svetlana G. Vorsanova, DSc., Director, Molecular-Cytogenetic Laboratory of Neuropsychiatric Diseases, Institute of Pediatrics and Children Surgery, Russian Ministry of Health, Taldom¬skaya str 2, 127 412 Moscow, Russia; Tel.: +7-095-484-19-48; Fax: +7-095-952-89-40; E-mail: y_yurov@yahoo. com
page: 81

REFERENCES

1. Smith GE, Berg JM. Down’s Anomaly. Edinburgh: Churchill Livingstone, 1976.

2. Hassold T, Jacobs P. Trisomy in man. Ann Rev Genet 1984; 18: 69-97.

3. Hassold T, Sherman S. Down syndrome: genetic recombination and the origin of the extra chromosome 21. Clin Genet 2000; 57(7): 95-100.

4. Petersen MB, Mikkelsen M. Nondisjunction in trisomy 21: origin and mechanisms. Cytogenet Cell Genet 2000; 91(1-4): 199-203.

5. Roizes G, Marcais B, Bellis M, Charlieu JP. The origin of non-disjunction in human chromosomes: a hypothesis. Genetics 1992; 11: 239-240.

6. Yurov YB, Selivanova HA, Deryagin GV. Use of cloned a-satellite DNA probes for the analysis of polymorphic heterochromatic regions of human chromosomes and parental origin of trisomy 21. Genetika (Moscow) 1991; 27(9): 1637-1647.

7. Maratou K, Siddique Y, Kessling A, Davies GE. Variation in alphoid DNA size and trisomy 21: a possible cause of nondisjunction. Hum Genet 2000; 106(5 ): 525-530.

8. Verma RS, Batish SD, Gogineni SK, Kleyman SM, Stetka DG. Centromeric alphoid DNA heteromorphisms of chromosome 21 by FISH-technique. Clin Genet 1997; 51(2): 91-93.

9. Soloviev IV, Yurov YB, Ioannou P, Georghiou A, Hadjimarcou M, Patsalis P, Roizes G, Sharonin VO, Kravets VS, Vorsanova SG. Identification and molecular-cytogenetic characterization of large subset of human plasmids, cosmids, PAC and YAC clones: the search of DNA probes for pre- and postnatal diagnosis. Cs Pediatr 1997; 52(7): 529-538.

10. Yurov YB, Soloviev IV, Vorsanova SG, Alexandrov IA, Sharonin VO, Monachov VV. DNA probes for pre- and postnatal diagnosis of chromosomal anomalies: a collection for FISH analysis. Cs Pediatr 1997; 52(7): 550-554.

11. Soloviev IV, Yurov YB, Vorsanova SG, Marcais B, Rogaev EI, Kapanadze BI, Brodiansky VM, Yankovsky NK, Roizes G. Fluorescent in situ hybridization analysis of a-satellite DNA in cosmid libraries specific for human chromosomes 13, 21 and 22. Rus J Genet 1998; 34(11): 1247-1255.

12. Pinkel D, Straume T, Gray JW. Cytogenetic analysis using quantitative, high-sensitive fluorescence hybridization. J Med Genet 1981; 18: 309-311.

13. Mikkelsen M, Poulsen H, Grinsted J, Lange A. Nondisjunction in trisomy 21: study of chromosomal heteromorphisms in 110 females. Ann Hum Genet 1980; 44(Pt 1): 17-28.

14. Jacobs PA, Mayer M. The origin of human trisomy: a study of heteromorphisms and satellites associations. Ann Hum Genet 1981; .45(Pt 4): 49-57.

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