UNUSUAL MANIFESTATION OF EXTRAOSSEOUS
EWING SARCOMA: REPORT OF 3 CASES
Ioannidou M.1,*, Tsotridou E.1, Samoladas E.2, Tragiannidis A.1, Kouskouras K.3,
Sfougaris D.4, Spyridakis I.5, Foroulis C.6, Galli-Tsinopoulou A.1, Hatzipantelis E.1
*Corresponding Author: MD Maria Ioannidou, St Kiriakidi 1, Children’s and Adolescent’s Hematology-
Oncology Unit of 2nd Department of Pediatrics, AUTh, AHEPA University General Hospital,
Thessaloniki, Greece. Zip code: 54621. Tel.: 00306942067923. E-mail: ioannidou@auth.gr
page: 77
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REFERENCES
1. Abboud A, Masrouha K, Saliba M, Haidar R, Saab
R, Khoury N, et al. Extraskeletal Ewing sarcoma:
Diagnosis, management and prognosis (Review).
Oncol Lett. 2021;21(5):1–6.
2. Ludwig JA. Ewing sarcoma: historical perspectives,
current state-of-the-art, and opportunities for
targeted therapy in the future. Curr Opin Oncol.
2008;20(4):412–8.
3. Galyfos G, Karantzikos GA, Kavouras N, Sianou A,
Palogos K, Filis K. Extraosseous Ewing Sarcoma:
Diagnosis, Prognosis and Optimal Management. Indian
J Surg. 2016;78(1):49–53.
4. Grier HE. The Ewing family of tumors. Ewing’s sarcoma
and primitive neuroectodermal tumors. Pediatr
Clin North Am. 1997;44(4):991–1004.
5. Applebaum MA, Worch J, Matthay KK, Goldsby R,
Neuhaus J, West DC, et al. Clinical features and outcomes
in patients with extraskeletal Ewing sarcoma.
Cancer. 2011;117(13):3027–32.
6. Cash T, McIlvaine E, Krailo MD, Lessnick SL, Lawlor
ER, Laack N, et al. Comparison of clinical features
and outcomes in patients with extraskeletal versus
skeletal localized Ewing sarcoma: A report from the
Children’s Oncology Group. Pediatr Blood Cancer.
2016;63(10):1771–9.
7. Rodriguez-Galindo C, Navid F, Khoury J, Krasin
Matthew. Ewing sarcoma family of tumors. In Pappo
A ed. Pediatric Bone and Soft Tissue Sarcomas. Berlin,
Heidelberg, Springer-Verlag, 2006: 181-217
8. Covelli HD, Beekman JF, Kingry RL. Extraskeletal
Ewing’s sarcoma: prolonged survival with recurrence
after operation. South Med J. 1980;73(9):1294–5.
9. Rud NP, Reiman HM, Pritchard DJ, Frassica FJ,
Smithson WA. Extraosseous Ewing’s sarcoma. A
study of 42 cases. Cancer. 1989;64(7):1548–53.
10. Paulussen M, Ahrens S, Dunst J, Winkelmann W,
Exner GU, Kotz R, et al. Localized Ewing tumor of
bone: final results of the cooperative Ewing’s Sarcoma
Study CESS 86. J Clin Oncol. 2001;19(6):1818–29.
11. Balamuth NJ, Womer RB. Ewing’s sarcoma. Lancet
Oncol. 2010;11(2):184–92.
12. Bacci G, Balladelli A, Forni C, Ferrari S, Longhi A,
Bacchini P, et al. Adjuvant and neoadjuvant chemotherapy
for Ewing sarcoma family tumors in patients
aged between 40 and 60: report of 35 cases and comparison
of results with 586 younger patients treated
with the same protocols in the same years. Cancer.
2007;109(4):780–6.
13. Dunst J, Schuck A. Role of radiotherapy in Ewing
tumors. Pediatr Blood Cancer. 2004;42(5):465–70.
14. Tefft M, Vawter GF, Mitus A. Paravertebral “round cell”
tumors in children. Radiology. 1969;92(7):1501–9.
15. Downing JR, Head DR, Parham DM, Douglass
EC, Hulshof MG, Link MP, et al. Detection of the
(11;22)(q24;q12) translocation of Ewing’s sarcoma
and peripheral neuroectodermal tumor by reverse
transcription polymerase chain reaction. Am J Pathol.
1993;143(5):1294–300.
16. Sorensen PH, Lessnick SL, Lopez-Terrada D, Liu
XF, Triche TJ, Denny CT. A second Ewing’s sarcoma
translocation, t(21;22), fuses the EWS gene to another
ETS-family transcription factor, ERG. Nat Genet.
1994;6(2):146–51.
17. Ahmad R, Mayol BR, Davis M, Rougraff BT. Extraskeletal
Ewing’s sarcoma. Cancer. 1999;85(3):725–31.
18. Parkin DM, Stiller CA, Nectoux J. International variations
in the incidence of childhood bone tumours. Int
J cancer. 1993;53(3):371–6.
19. Geens L, Van Robays J, Geert V, Van Der Speeten K.
An unusual location of extraosseous ewing’s sarcoma.
Case Rep Oncol. 2013;6(2):293–302.
20. Tanida S, Tanioka F, Inukai M, Yoshioka N, Saida
Y, Imai K, et al. Ewing’s sarcoma/peripheral primitive
neuroectodermal tumor (pPNET) arising in the
omentum as a multilocular cyst with intracystic hemorrhage.
J Gastroenterol. 2000;35(12):933–40.
21. Maeda M, Tsuda A, Yamanishi S, Uchikoba Y, Fukunaga
Y, Okita H, et al. Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child. Pediatr
Blood Cancer. 2008;50(1):180–3.
22. Buffoni I, Nuri H, Pome’ G, Sementa AR, Stagnaro
N, Barra S, et al. Pediatric Extraskeletal Ewing Sarcoma
Originating in the Heart: A Case Report and
Review of the Literature. J Pediatr Hematol Oncol.
2021;43(4):147–51.
23. Park J-Y, Lee S, Kang HJ, Kim H-S, Park S-Y. Primary
Ewing’s sarcoma-primitive neuroectodermal
tumor of the uterus: a case report and literature review.
Gynecol Oncol. 2007;106(2):427–32.
24. Ling X, Tong J, Wang L, Yao C, Chen Z. Primary
pulmonary Ewing’s sarcoma: rare cause of massive
hemothorax in a young girl-case report. BMC Pediatr.
2021;21(1):194.
25. Mehra S, Atwal SS, Garga UC. Primary Pulmonary
Ewing’s Sarcoma: Rare Cause of Superior Vena
Cava Syndrome in Children. J Clin Diagn Res.
2014;8(8):RD05-6.
26. Mathew D, Prince DN, Mahomed N. Extra-skeletal
Ewing Sarcoma of the chest wall in a child. SA J
Radiol. 2019;23(1):1733.
27. Sharma A, Sethi N, Saini S, Pandia K, Jangir R. Primary
Ewings sarcoma in liver - A rare case report
with review of literature. Indian J Pathol Microbiol.
2021;64(Supplement):S136–9.
28. Shadhu K, Ramlagun-Mungur D, Ping X-C. Ewing
sarcoma of the jejunum: A case report and literature
review. World J Gastrointest Surg. 2021;13(5):507-515.
29. Shek TW, Chan GC, Khong PL, Chung LP, Cheung
AN. Ewing sarcoma of the small intestine. J Pediatr
Hematol Oncol. 2001;23(8):530–2.
30. Van den Berg H, Heinen RC, van der Pal HJ, Merks
JHM. Extra-osseous Ewing sarcoma. Pediatr Hematol
Oncol. 2009;26(4):175–85.
31. Casali PG, Bielack S, Abecassis N, Aro HT, Bauer
S, Biagini R, et al. Bone sarcomas: ESMO-Paed-
Can-EURACAN Clinical Practice Guidelines for
diagnosis, treatment and follow-up. Ann Oncol.
2018;29(Suppl 4):iv79–95.
32. Biermann JS. Updates in the treatment of bone cancer.
J Natl Compr Canc Netw. 2013;11(5 Suppl):681–3.
33. El Weshi A, Allam A, Ajarim D, Al Dayel F, Pant R, Bazarbashi
S, et al. Extraskeletal Ewing’s sarcoma family
of tumours in adults: analysis of 57 patients from a
single institution. Clin Oncol. 2010;22(5):374–81.
34. Kontny U. Regulation of apoptosis and proliferation
in Ewing’s sarcoma--opportunities for targeted
therapy. Hematol Oncol. 2006;24(1):14–21.
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