ASSOCIATION BETWEEN INHERITED THROMBOPHILIA
IN PREGNANCY AND MICRONUCLEUS FREQUENCY
IN PERIPHERAL BLOOD LYMPHOCYTES
Šošić GM1,*, Jović N2,5, Rakić B3, Dimitrijević A2,4, Varjačić M2,5
*Corresponding Author: Gordana M. Šošić, B.Sc., Department of Cytogenetic Diagnosis, Obstetrics and Gynecology
Clinic, Clinical Center “Kragujevac,” 30 Zmaj Jovina Street, 3400 Kragujevac, Serbia. Tel: +381-63-835-66-24.
Fax: +381-34-37-00-73. Email: gordana.sosic.2011.02@gmail.com
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REFERENCES
1. Veerachari U, Venkatesh S, Yadav A, Narayanappa R.
Biomonitoring genetic instability in normal healthy
population using a simple cytogenetic marker – micronucleus
test. Int Multidiscip Res J. 2011; 1/2: 01-09.
2. Šošić GM, Varjačić M. Uticaj fizičke aktivnosti na
stepen hromozomskih aberacija. TIMS Acta. 2015;
9(1): 49-61.
3. Kopjar N, Kasuba V, Milić M, Rozgaj R, Zeljezić
D, Gajski G, et al. Normal and cut-off values of the
cytokinesis-block micronucleus assay on peripheral
blood lymphocytes in the Croatian general population.
Arh Hig Rada Toksikol. 2010; 61(2): 219-234.
4. Fenech M, Kirsch-Volders M, Natarajan AT, Surralles
J, Crott JW, Parry J, et al. Molecular mechanisms of
micronucleus, nucleoplasmic bridge and nuclear bud
formation in mammalian and human cells. Mutagenesis.
2011; 26(1): 125-132.
5. Luzhna L, Kathiria P, Kovalchuk O. Micronuclei
in genotoxicity assessment: From genetics to epigenetics
and beyond. Front Genet. 2013; 4: 131.
6. Fenech Ì. Cytokinesis-block micronucleus cytome
assay. Nat Protoc. 2007; 2(5): 1084-1104.
7. Heddle JA, Fenech M, Hayashi M, MacGregor JT.
Reflections on the development of micronucleus assays.
Mutagenesis. 2011; 26(1): 3-10.
8. Surowy H, Rinckleb A, Luedeke M, Stuber M,
Wecker A, Varga D, et al. Heritability of baseline
and induced micronucleus frequencies. Mutagenesis.
2011; 26(1): 111-117.
9. Fenech M, Bonassi S. The effect of age, gender,
diet and lifestyle on DNA damage measured using
micronucleus frequency in human peripheral blood
lymphocytes. Mutagenesis. 2011; 26(1): 43-49.
10. Ferraz GA, Costa Neto AdeO, Cerqueira En deMM,
Meireles JRC. Effects of age on the frequency of
micronuclei and degenerative nuclear abnormalities.
Rev Bras Geriatr Gerontol. 2016; 19(4): 627-634.
11. Milosević-Djordjević O, Grujicić D, Vasković Z,
Marinković D. High micronucleus frequency in
peripheral blood lymphocytes of untreated cancer
patients irrespective of gender, smoking and cancer
sites. Tohoku J Exp Med. 2010; 220(2): 115-120.
12. Petrozzi L, Lucetti C, Scarpato R, Gambaccini G, Trippi
F, Bernardini S, et al. Cytogenetic alterations in lymphocytes
of Alzheimer’s disease and Parkinson’s disease
patients. Neurol Sci. 2002; 23(Suppl 2): S97-S98.
13. Scarpato R, Verola C, Fabiani B, Bianchi V, Saggese
G, Federico G. Nuclear damage in peripheral lymphocytes
of obese and overweight Italian children
as evaluated by the-H2AX focus assay and micronucleus
test. FASEB J. 2011; 25(2): 685-693.
14. Bhat MA, Mahajan N, Gandhi G. DNA and chromosomal
damage in coronary artery disease patients.
EXCLI J. 2013; 12: 872-884.
15. Torres-Bugarín O, Macriz Romero N, Ramos Ibarra
ML, Flores-García A, Valdez Aburto P, Zavala-Cerna
MG. Genotoxic effect in autoimmune diseases evaluated
by the micronucleus test assay: Our experience and
literature review. Biomed Res Int. 2015; 2015: 194031.
16. Andreassi MG, Barale R, Iozzo P, Picano E. The
association of micronucleus frequency with obesity,
diabetes and cardiovascular disease. Mutagenesis.
2011; 26(1): 77-83.
17. Silva-Grecco RL, Navarro GC, Cruz RM, Balarin
MA. Micronucleated lymphocytes in parents of Down
syndrome children. Braz J Med Biol Res. 2012; 45(7):
573-577.
18. Holland N, Bolognesi C, Kirsch-Volders M, Bonassi
S, Zeiger E, Knasmueller S, et al. The micronucleus
assay in human buccal cells as a tool for biomonitoring
DNA damage: The HUMN project perspective on
current status and knowledge gaps. Mutat Res. 2008;
659(1-2): 93-108.
19. Furness DL, Dekker GA, Hague WM, Khong TY,
Fenech MF. Increased lymphocyte micronucleus fre quency in early pregnancy is associated prospectively
with pre-eclampsia and/or intrauterine growth restriction.
Mutagenesis. 2010; 25(5): 489-498.
20. Fenech M. Micronuclei and their association with
sperm abnormalities, infertility, pregnancy loss, preeclampsia
and intra-uterine growth restriction in humans.
Mutagenesis. 2011; 26(1): 63-67.
21. Pristov JB, Spasojevic I, Mikovic Ž, Mandic V,
Cerovic N, Spasic M. Antioxidative defense enzymes
in placenta protect placenta and fetus in inherited
thrombophilia from hydrogen peroxide. Oxid Med
Cell Longev. 2009; 2(1): 14-18.
22. Aracic N, Roje D, Drmic Hofman I, Capkun V, Stefanovic
V. Low molecular weight heparin treatment and
impact of inherited thrombophilia type in pregnancies
with previous adverse outcome. J Matern Fetal
Neonatal Med. 2015; 28(3): 306-310.
23. Fenech M, Chang WP, Kirsch-Volders M, Holland N,
Bonassi S, Zeiger E; HUman MicronNucleus project.
HUMN project: Detailed description of the scoring
criteria for the cytokinesis-block micronucleus assay
using isolated human lymphocyte cultures. Mutat
Res. 2003; 534(1-2): 65-75.
24. Turki RF, Assidi M, Banni HA, Zahed HA, Karim S,
Schulten HJ, et al. Associations of recurrent miscarriages
with chromosomal abnormalities, thrombophilia
allelic polymorphisms and/or consanguinity
in Saudi Arabia. BMC Med Genet. 2016; 17(Suppl
1): 15-23.
25. Toljic M, Egic A, Munjas J, Karadzov Orlic N,
Milovanovic Z, Radenkovic A, et al. Increased oxidative
stress and cytokinesis-block micronucleus
cytome assay parameters in pregnant women with
gestational diabetes mellitus and gestational arterial
hypertension. Reprod Toxicol. 2017; 71: 55-62.
26. Nefic H, Musanovic J, Kurteshi K, Prutina E, Turcalov
E. The effects of sex, age and cigarette smoking
on micronucleus and degenerative nuclear alteration
frequencies in human buccal cells of healthy Bosnian
subjects. Saglik Bilim Derg. 2013; 3(3): 196-204.
27. Fenech M, Holland N, Zeiger E, Chang WP, Burgaz S,
Thomas P, et al. The HUMN and HUMNxL international
collaboration projects on human micronucleus
assays in lymphocytes and buccal cells – past, present
and future. Mutagenesis. 2011; 26(1): 239-245.
28. Zergollen Lj i. suradnici, Malformacijski sindromi
uzrokovani vanjski činiocima, Sambolek-Hrbić E.
Medicinska Genetika, vol. 1. Zagreb, Hrvatska:
Školska Knjiga. 1987: 150-159.
29. Veazey KJ, Carnahan MN, Muller D, Miranda RC,
Golding MC. Alcohol-induced epigenetic alterations
to developmentally crucial genes regulating neural
stemness and differentiation. Alcohol Clin Exp Res.
2013; 37(7): 1111-1122.
30. Brocardo PS, Gil-Mohapel J, Christie BR. The role of
oxidative stress in fetal alcohol spectrum disorders.
Brain Res Rev. 2011; 67(1-2): 209-225.
31. Wu D, Cederbaum AI. Alcohol, oxidative stress, and
free radical damage. Alcohol Res Health. 2003; 27(4):
277-284.
32. Singh S, Saini M, Yadav AS. Elevated frequencies of
micronuclei and other nuclear anomalies in alcoholic
subjects. J Entomol Zool Stud. 2015; 3(2): 243-245.
33. Demirhan O, Tastemir D. Cytogenetic effects of ethanol
on chronic alcohol users. Alcohol Alcohol. 2008;
43(2): 127-136.
34. Santovito A, Cervella P, Delpero M. Evidence of
genotoxicity in lymphocytes of non-smoking alcoholics.
Mol Biol Rep. 2015; 42(1): 53-59.
35. Benassi-Evans B, Fenech M. Chronic alcohol exposure
induces genome damage measured using the
cytokinesis-block micronucleus cytome assay and
aneuploidy in human B lymphoblastoid cell lines.
Mutagenesis. 2011; 26(3): 421-429.
36. Kacprzak M, Chrzanowska M, Beata Skoczylas B,
Moczulska H, Borowiec M, Sieroszewski P. Genetic
causes of recurrent miscarriages. Ginekologia Polska.
2016; 87(10): 722-726.
37. Šošić GM, Sretenović S, Varjačić M. P-043: Genes
polymorphism FV Leiden G1691A, FII G20210A,
MTHFR C677T and PAI-1 5G/4G in patients with
miscarriages and inherited thrombophilia – experience
from our clinic. (Papers and Abstracts of the
7th International Symposium on Women’s Health Issues
in Thrombosis and Haemostastis, held on March
3-5, 2017 at Barcelona, Spain.) Thromb Res. 2017;
151(Suppl 1): S122-S123.
38. Karsli MF, Baser E, Seckin KD, Yeral Mİ, Togrul C,
Ugur M. The impact of inherited thrombophilia on
first trimester combined aneuploidy screening test parameters.
J Matern Fetal Neonatal Med. 2014; 27(4):
346-349.
39. Cıkman MS, Seckin KD, Karslı MF, Baser E, Cıkman
DI, Cicek MN. The effect of inherited thrombophilia
on second trimester combined aneuploidy screening
test markers. Arch Gynecol Obstet. 2015; 291(4):
787-790.
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