Balkan Journal of Medical Genetics

ORGANOCHLORIDE PESTICIDES IN MACEDONIAN GIRLS WITH PREMATURE SEXUAL DEVELOPMENT
Krstevska-Konstantinova M1,*, Kocova M1, Charlier C2, Bourguignon JP3
*Corresponding Author: Dr. Marina Krstevska Konstantinova, Pediatric Clinic, Department of Endocrinology and Genetics, Medical Faculty, Vodnjanska 17, 1000 Skopje, Republic of Macedonia; Tel.: +389-2-314-7474; Fax: +389-2-3225-809; E-mail: marina@lancom.com.mk
page: 43

CONCLUSIONS

Our study showed that Macedonian girls with PSD do not have increased levels of p,p’-DDE and lindane, which could be a reason for their sexual precocity, compared to the control group. Girls in the Republic of Macedonia with PSD have similar levels of pesticides in their serum as the adopted immigrant girls in our Belgian study [3]. Further studies are needed to determine if eventual pubertal disturbances have occurred in girls from the Republic of Macedonia who had moved to a western country.

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