
ROLE OF THE CYP1A2 GENE POLYMORPHISM ON
EARLY AGEING FROM OCCUPATIONAL EXPOSURE Eshkoor SA1,2,*, Ismail P1, Rahman SA2, Moin S2, Adon MY3 *Corresponding Author: Dr. Sima A. Eshkoor, Institute of Gerontology, Faculty of Medicine and Health Sciences,
Universiti Putra Malaysia (UPM), 43400, Malaysia; Tel.: +60-129-797-812; Fax: +60-389-472-744;
E-mail: simaataolahi@yahoo.com page: 45
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REFERENCES
1. Vijg J. Somatic mutations and aging: a re-evaluation.
Mutat Res. 2000; 447(1): 117-135.
2. Wojda A, Witt M. Manifestations of aging at the
cytogenetic level. J Appl Genet. 2003; 44(3):
383-399.
3. Harman D. The aging process: major risk factor
for disease and death. Proc Nat Acad Sci USA.
1991; 88(12): 5360-5363.
4. Pande M, Amos CI, Osterwisch DR, Chen J,
Lynch PM, Broaddus R, et al. Genetic variation
in genes for the xenobiotic-metabolizing enzymes
CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1
and susceptibility to colo-rectal cancer in Lynch
Syndrome. Cancer Epidemiol Bio-markers Prev.
2008; 17(9): 2393-2399.
5. Lautraite S, Musonda AC, Doehmer J, Edwards
GO, Chipman JK. Flavonoids inhibit genetic toxicity
produced by carcinogens in cells expressing
CYP1A2 and CYP1A1. Mutagenesis. 2002;
17(1): 45-53.
6. Al Zabadi H, Ferrari L, Laurent AM, Tiberguent
A, Paris C, Zmirou-Navier D. Biomonitoring of
complex occupational exposures to carcinogens:
the case of sewage workers in Paris. BMC Cancer.
2008; 8(1): 67-77.
7. Vainio H. Use of biomarkers in risk assessment.
Int J Hyg Environ Health. 2001; 204(2-3): 91-102.
8. Martino-Roth MG, Viegas J, Amaral M, Oliveira
L, Ferreira FLS, Erdtmann B. Evaluation of genotoxicity
through micronuclei test in workers of
car and battery repair garages. Genet Mol Biol.
2002; 25(4): 495-500.
9. Eshkoor SA, Ismail P, Rahman SA, Moin S. Does
GSTP1 polymorphism contribute to genetic damage
caused by ageing and occupational exposure?
Arh Hig Rada Toksikol. 2011; 62(4): 291-298.
10. Cawthon RM. Telomere measurement by quantitative
PCR. Nucleic Acids Res. 2002; 30(10): e47.
11. Nakajima M, Yokoi T, Mizutani M, Kinoshita
M, Funayama M, Kamataki T. Genetic polymorphism
in the 5’-flanking region of human CYP1A2
gene: effect on the CYP1A2 inducibility
in humans. J Biochem. 1999; 125(4): 803-808.
12. Pavanello S, Pulliero A, Lupi S, Gregorio P, Clonfero
E. Influence of the genetic polymorphism in
the 5’-noncoding region of the CYP1A2 gene on
CYP1A2 phenotype and urinary mutagenicity in
smokers. Mutat Res. 2005; 587(1-2): 59-66.
13. Hashizumea T, Yoshitomia S, Asahia S, Matsumuraa
S, Chatania F, Odab H. In vitro micronucleus
test in HepG2 transformants expressing a
series of human cyto-chrome P450 isoforms with
chemicals requiring metabolic activation. Mutat
Res. 2009; 677(1-2): 1-7.
14. da Silva J, Moraes CR, Heuser VD, Andrade VM,
Silva FR, Kvitko K, et al. Evaluation of genetic
damage in a Brazilian population occupationally
exposed to pesticides and its correlation with
polymorphisms in metabolizing genes. Mutagenesis.
2008; 23(5): 415-422.
15. Castorena-Torres F, Mendoza-Cantu A, de Leon
MB, Cisneros B, Zapata-Perez O, López-Carrillo
L, et al. CYP1A2 phenotype and genotype in a
population from the carboniferous region of Coahuila,
Mexico. Toxicol Lett. 2005; 156(3): 331-339.
16. Bageman E, Ingvar C, Rose C, Jernstrom H.
Coffee consumption and CYP1A2*1F genotype
modify age at breast cancer diagnosis and estrogen
receptor status. Cancer Epidemiol Biomarkers
Prev. 2008; 17(4): 895-901.
17. Iba MM, Fung J. Pulmonary CYP1A1 and CYP1A2
levels and activities in adult male and female
offspring of rats exposed during gestation
and lactation to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Biochem Pharmacol. 2001; 62(5): 617-626.
18. Sata F, Yamada H, Suzuki K, Saijo Y, Kato EH,
Morikawa M, et al. Caffeine intake, CYP1A2
polymorphism and the risk of recurrent pregnancy
loss. Mol Hum Reprod. 2005; 11(5): 357-360.
19. Kirsch-Volders M, Mateuca RA, Roelants M,
Tremp A, Zeiger E, Bonassi S, et al. The effects
of GSTM1 and GSTT1 polymorphisms on micronucleus
frequencies in human lymphocytes in
vivo. Cancer Epi-demiol Biomarkers Prev. 2006;
15(5): 1038-1042.
20. Garte S, Taioli E, Popov T, Kalina I, Sram R,
Farmer P. Role of GSTT1 deletion in DNA oxidative
damage by exposure to polycyclic aromatic
hydrocarbons in humans. Int J Cancer. 2006;
120(11): 2499-2503.
21. Palma S, Cornetta T, Padua L, Cozzi R, Appolloni
M, Ievoli E, et al. Influence of glutathione
S-transferase polymorphisms on genotoxic effects
induced by tobacco smoke. Mutat Res. 2007;
633(1): 1-12.
22. Zhan P, Wang J, Zhang Y, Qiu LX, Zhao SF, Qian
Q, et al. CYP2E1 Rsa I/Pst I polymorphism is
associated with lung cancer risk among Asians.
Lung Cancer. 2010; 69(1): 19-25.
23. Pinto D, Ceballos JM, Garcia G, Guzman P, Del
Razo LM, Vera E, et al. Increased cytogenetic
damage in outdoor painters. Mutat Res. 2000;
467(2): 105-111.
24. Manikantan P, Balachandar V, Sasikala K. DNA
Damage in workers occupationally exposed to
lead, using comet assay. Int J Biol. 2010; 2(1):
103-110.
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