
METABOLIC GENE POLYMORPHISMS
ASSOCIATED WITH ATOPIC BRONCHIAL ASTHMA
Ivaschenko TE1, Sideleva OG1, Zelenina LA2, Antonova EA2,
Ostankova JV1, Aseev MV1, Baranov VS1
*Corresponding Author: Professor Dr. Vladislav S. Baranov, Ott’s Institute of Obstetrics/Gynecology, Russian Academy of Medical Sciences, Mendeleevskaya line 3, 199034 St. Petersburg, Russia; Tel/Fax: +07(812) 3280487 E-mail: baranov@vb2475.spb.edu page: 23
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REFERENCES
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2. Adra CN, Mao XQ, Kawada H, Gao PS, Korzycka B, Donate JL, Shaldon SR, Coull P, Dubowitz M, Enomoto T, Ozawa A, Syed SA, Horiuchi T, Khaeraja R, Khan R, Lin SR, Flinter F, Beales P, Hagihara A, Inoko H, Shirakawa T, Hopkin JM. Chromosome 11q13 and atopic asthma. Clin Genet 1999; 55 (6): 431-437.
3. Nicolaides NC, Holroyd KJ, Ewart SL, Eleff SM, Kiser MB, Dragwa CR, Sullivan CD, Grasso L, Zhang LY, Messler CJ, Zhou T, Kleeberger SR, Buetow KH, Levitt RC. Interleukin 9: a candidate gen for asthma. Proc Natl Acad Sci USA 1997; 94 (24): 13175-13180.
4. Weiss ST. Issues in phenotype assessment. In: The Genetics of Asthma, Liggett SB, Meyers DA (eds). Marcel Dekker, Inc., New York, NY, USA, 1996; 401-419.
5. Barnes PJ. Reactive oxygen species and airway inflammation. Free Rad Biol Med 1990; 9: 235-243.
6. Smith C, Harrison D. Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema. The Lancet 1997; 350: 630-633.
7. Gawonska-Sklarz B, Luszawska-Kutrzeba T, Czaja-Bulsa G, Kurzawski G. Relationship between acetylation polymorphism and risk of atopic diseases. Clin Pharmacol Ther 1999; 5: 562-569.
8. Fryer AA, Bianco A, Hepple M, Jones PW, Strange RC, Spiteri MA. Polymorphism at the glutathione-S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma. Am J Respir Crit Care Med 2000; 161 (5): 1437-1442.
9. Hayes JD, Strange RC. Potential contribution of the glutathione-S-transferase supergene family to resistance to oxidative stress. Free Rad Res Commun 1995; 22: 193-207.
10. Brockmoller J, Cascorbi I, Kerb R, Roots I. Combined analysis of inherited polymorphisms in arilamine N-acetyltransferase 2, glutathione-S-transferases M1 and T1,
microsomal expoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. Cancer Res 1996; 56: 3915-3925.
11. Ali-Osman F, Akande O, Antoun G, Mao J-X, Boulamwini J. Molecular cloning, characterization, and expression of Escherichiacoli of full-length cDNAs of three
human glutathione-S-transferase pi gene variants. J Biol Chem 1997; 272: 10004-10012.
12. Sideleva OG, Ivaschenko TE, Gembitskaya TE, Petrova MA, Orlov AV, Baranov VS. Positive association atopic bronchial asthma with polymorphisms of glutathione-s-transferase mu and theta genes. Balkan J Med Genet 2000; 3 (3): 3-6.
13. Chasseaud LF. The role of glutathione S-transferase in the metabolism of chemical carcinogenes and other electrophilic agents. Adv Cancer Res 1979; 29:175-274.
14. Laisney V, Nguyen VC, Gross MS, Frezal J. Human genes for glutathione S-tranferases. Hum Genet 1984; 68 (3):221-227.
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