A NEW CLOCK IS RUNNING FOR MULTIPLE MYELOMA: CIRCADIAN CLOCK PROTEIN-PERIOD 3 (PER-3) POLYMORPHISM
Serin I.1,*, Pehlivan S.2, Demir I.3, Oyacı Y.2, Pehlivan M.3
*Corresponding Author: Istemi Serin, M.D., University of Health Sciences, Istanbul Training and Research Hospital, Department of Hematology, Org. Nafiz GURMAN Cad., Fatih, 34098 tel.: +90 532 3172393, e-mail: serinistemi@hotmail.com
page: 37

REFERENCES

1. Rajkumar SV. Multiple myeloma: 2020 update on diagnosis, risk-stratification and management [published correction appears in Am J Hematol. 2020 Nov; 95(11):1444]. Am J Hematol. 2020;95(5):548-567. doi:10.1002/ajh.25791 2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020; 70(1): 7-30. doi:10.3322/caac.21590 3. Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Melton LJ. 3rd. Incidence of multiple myeloma in Olmsted County, Minnesota: Trend over 6 decades. Cancer. 2004; 101(11) :2667-2674. doi:10.1002/cncr.20652 4. Scheiermann C, Gibbs J, Ince L, Loudon A. Clocking in to immunity. Nat Rev Immunol. 2018; 18(7): 423-437. doi:10.1038/s41577-018-0008-4 5. Labrecque N, Cermakian N. Circadian Clocks in the Immune System. J Biol Rhythms. 2015; 30(4): 277- 290. doi:10.1177/0748730415577723 6. Guess J, Burch JB, Ogoussan K, Armstead CA, Zhang H, Wagner S et al. Circadian disruption, Per3, and human cytokine secretion. Integr Cancer Ther. 2009; 8(4): 329-336. doi:10.1177/1534735409352029 7. Ebisawa T, Uchiyama M, Kajimura N, Mishima K, Kamei Y, Katoh M et al. Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome. EMBO Rep. 2001; 2(4): 342-346. doi:10.1093/embo-reports/kve070 8. Helvaci N, Oguz SH, Kabacam S, Karabulut E, Akbiyik F, Alikasifoglu M et al. Clock gene PERIOD3 polymorphism is associated with susceptibility to Graves’ disease but not to Hashimoto’s thyroiditis. Chronobiol Int. 2019; 36(10): 1343-1350. doi:1 0.1080/07420528.2019.1642909 9. Zhu Y, Brown HN, Zhang Y, Stevens RG, Zheng T. Period3 structural variation: a circadian biomarker associated with breast cancer in young women. Cancer Epidemiol Biomarkers Prev. 2005; 14(1): 268-270. 10. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988; 16(3): 1215. doi:10.1093/nar/16.3.1215 11. Nursal A, Cetinay Aydin P, Uysal M, Pehlivan M, Oyacı Y, Pehlivan S. PER3 VNTR variant and susceptibility to smoking status/substance use disorder in a Turkish population. Archives of Clinical Psychiatry (São Paulo). 47. 10.1590/0101-60830000000235. 12. Dagmura H, Yiğit S, Nursal AF, Duman E, Gumusay O. Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer. Genet Test Mol Biomarkers. 2021; 25(2): 124-130. doi:10.1089/gtmb.2020.0179 13. Geng P, Ou J, Li J, Wang N, Xie G, Sa R et al. Genetic association between PER3 genetic polymorphisms and cancer susceptibility: a meta-analysis. Medicine (Baltimore). 2015; 94(13): e568. doi:10.1097/ MD.0000000000000568 14. Karantanos T, Theodoropoulos G, Gazouli M, Vaiopoulou A, Karantanou C, Stravopodis DJ et al. Association of the clock genes polymorphisms with colorectal cancer susceptibility. J Surg Oncol. 2013 Dec; 108(8): 563-7. doi: 10.1002/jso.23434. 15. Alexander M, Burch JB, Steck SE, Chen CF, Hurley TG, Cavicchia P et al. Case-control study of the PERIOD3 clock gene length polymorphism and colorectal adenoma formation. Oncol Rep. 2015; 33(2): 935- 941. doi:10.3892/or.2014.3667 16. Gutiérrez-Monreal MA, Villela L, Baltazar S, Perfecto- Avalos Y, Cardineau GA, Scott SP. A PER3 polymorphism is associated with better overall survival in diffuse large B-cell lymphoma in Mexican population. Cancer Biomark. 2015; 15(5): 699-705. doi:10.3233/CBM-150511 17. Yang MY, Lin PM, Hsiao HH, Hsu JF, Lin HY, Hsu CM et al. Up-regulation of PER3 Expression Is Correlated with Better Clinical Outcome in Acute Leukemia. Anticancer Res. 2015; 35(12): 6615-6622. 18. Motivala SJ, Levin MJ, Oxman MN, Irwin MR. Impairments in health functioning and sleep quality in older adults with a history of depression. J Am Geriatr Soc. 2006; 54(8): 1184-1191. doi:10.1111/j.1532- 5415.2006.00819.x 19. Vgontzas AN, Chrousos GP. Sleep, the hypothalamicpituitary- adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders. Endocrinol Metab Clin North Am. 2002; 31(1): 15-36. doi:10.1016/s0889-8529(01)00005-6 20. Vgontzas AN, Zoumakis M, Bixler EO, Lin HM, Prolo P, Vela-Bueno A et al. Impaired nighttime sleep in healthy old versus young adults is associated with elevated plasma interleukin-6 and cortisol levels: physiologic and therapeutic implications. J Clin Endocrinol Metab. 2003; 88(5): 2087-2095. doi:10.1210/jc.2002-021176 21. Ria R, Melaccio A, Racanelli V, Vacca A. Anti-VEGF Drugs in the Treatment of Multiple Myeloma Patients. J Clin Med. 2020; 9(6): 1765. Published 2020 Jun 6. doi:10.3390/jcm9061765



Number 27
VOL. 27 (2), 2024
Number 27
VOL. 27 (1), 2024
Number 26
Number 26 VOL. 26(2), 2023 All in one
Number 26
VOL. 26(2), 2023
Number 26
VOL. 26, 2023 Supplement
Number 26
VOL. 26(1), 2023
Number 25
VOL. 25(2), 2022
Number 25
VOL. 25 (1), 2022
Number 24
VOL. 24(2), 2021
Number 24
VOL. 24(1), 2021
Number 23
VOL. 23(2), 2020
Number 22
VOL. 22(2), 2019
Number 22
VOL. 22(1), 2019
Number 22
VOL. 22, 2019 Supplement
Number 21
VOL. 21(2), 2018
Number 21
VOL. 21 (1), 2018
Number 21
VOL. 21, 2018 Supplement
Number 20
VOL. 20 (2), 2017
Number 20
VOL. 20 (1), 2017
Number 19
VOL. 19 (2), 2016
Number 19
VOL. 19 (1), 2016
Number 18
VOL. 18 (2), 2015
Number 18
VOL. 18 (1), 2015
Number 17
VOL. 17 (2), 2014
Number 17
VOL. 17 (1), 2014
Number 16
VOL. 16 (2), 2013
Number 16
VOL. 16 (1), 2013
Number 15
VOL. 15 (2), 2012
Number 15
VOL. 15, 2012 Supplement
Number 15
Vol. 15 (1), 2012
Number 14
14 - Vol. 14 (2), 2011
Number 14
The 9th Balkan Congress of Medical Genetics
Number 14
14 - Vol. 14 (1), 2011
Number 13
Vol. 13 (2), 2010
Number 13
Vol.13 (1), 2010
Number 12
Vol.12 (2), 2009
Number 12
Vol.12 (1), 2009
Number 11
Vol.11 (2),2008
Number 11
Vol.11 (1),2008
Number 10
Vol.10 (2), 2007
Number 10
10 (1),2007
Number 9
1&2, 2006
Number 9
3&4, 2006
Number 8
1&2, 2005
Number 8
3&4, 2004
Number 7
1&2, 2004
Number 6
3&4, 2003
Number 6
1&2, 2003
Number 5
3&4, 2002
Number 5
1&2, 2002
Number 4
Vol.3 (4), 2000
Number 4
Vol.2 (4), 1999
Number 4
Vol.1 (4), 1998
Number 4
3&4, 2001
Number 4
1&2, 2001
Number 3
Vol.3 (3), 2000
Number 3
Vol.2 (3), 1999
Number 3
Vol.1 (3), 1998
Number 2
Vol.3(2), 2000
Number 2
Vol.1 (2), 1998
Number 2
Vol.2 (2), 1999
Number 1
Vol.3 (1), 2000
Number 1
Vol.2 (1), 1999
Number 1
Vol.1 (1), 1998

 

 


 About the journal ::: Editorial ::: Subscription ::: Information for authors ::: Contact
 Copyright © Balkan Journal of Medical Genetics 2006