TWO NOVEL CEBPA MUTATIONS IN A TURKISH PATIENT
WITH ACUTE MYELOID LEUKEMIA
Tokgun PE, Alay MT, Atli Tekin S, Güler N, Tokgun O, Demiray A,
Karagenc N, Durak T, Celik B, Akca H
*Corresponding Author: Professor Hakan Akca, Department of Medical Genetics, School of Medicine,
Pamukkale University, Çamlaraltı, Denizli, Turkey 20070. Tel.: +90-258-296-48-04. Fax: +90-258-296-
17-65. E-mail: hakca@pau.edu.tr
page: 99
|
|
REFERENCES
1. De Kouchkovsky I, Abdul-Hay M. Acute myeloid
leukemia: A comprehensive review and 2016 update.
Blood Cancer J. 2016; 6(7): e441.
2. Lin P, Falini B. Acute myeloid leukemia with recurrent
genetic abnormalities other than translocations.
Am J Clin Pathol. 2015; 144(1): 19-28.
3. Schnittger S, Schoch C, Dugas M. Analysis of FLT3
length mutations in 1003 patients with acute myeloid
leukemia: Correlation to cytogenetics, FAB subtype,
and prognosis in the AMLCG study and usefulness
as a marker for the detection of minimal residual
disease. Blood. 2002; 100(1): 59-67.
4. Li GX, Wang L, Yaghmour B, Ramshingh G, Yaghmour
G. The role of FLT3 inhibitors as maintenance therapy
following hematopoietic stem cell transplant. Leuk
Res Rep. 2018; 10: 26-36.
5. Thiede C, Koch S, Creutzig E, Steudel C, Illmer T, Schaich
M, et al. Prevalence and prognostic impact of NPM1
mutations in 1485 adult patients with acute myeloid
leukemia (AML). Blood. 2006; 107(10): 4011-4020.
6. Geletu M, Balkhi MY, Peer Zada AA Christopeit M,
Pulikkan JA, Trivedi AK, et al. Target proteins of C/
EB Pap30 in AML: C/EBPap30 enhances sumoylation
of C/EB Pap42 via up-regulation of Ubc9. Blood.
2007; 110(9): 3301-3309.
7. Pastore F, Kling D, Hoster E, Dufour A, Konstandin
NP, Schneider S, et al. Long-term follow-up of cytogenetically
normal CEBPA-mutated AML. J Hematol
Oncol. 2014; 7(1): 1-8.
8. Leroy H, Roumier C, Huyghe P, Biggio V, Fenaux P,
Preudhomme C. CEBPA point mutations in hematological
malignancies. Leukemia. 2005; 19(3): 329-334. 9. Hughes JM, Legnini I, Salvatori B, Masciarelli S,
Marchioni M, Fazi F, et al. C/EBPα-p30 protein induces
expression of the oncogenic long non-coding
RNA UCA1 in acute myeloid leukemia. Oncotarget.
2015; 6(21): 18534-18544.
10. Tawana K, Rio-Machin A, Preudhomme C, Fitzgibbon
J. Familial CEBPA-mutated acute myeloid leukemia.
Semin Hematol. 2017; 54(2): 87-93.
11. Kim S, Kim DH, Jang JH, Jung CW, Jang MA, Ki
CS, et al. Novel mutations in CEBPA in Korean patients
with acute myeloid leukemia with a normal
karyotype. Ann Lab Med. 2012; 32(2): 153-157.
12. Ram J, Flamm G, Balys M, Sivagnanalingam U,
Rothberg PG, Iqbal A, et al. Index case of acute myeloid
leukemia in a family harboring a novel CEBPA
germ line mutation. Blood Adv. 2017; 1(8): 500-503.
|
|
|
|
 |
Number 27
VOL. 27 (2), 2024 |
Number 27
VOL. 27 (1), 2024 |
Number 26
Number 26 VOL. 26(2), 2023 All in one |
Number 26
VOL. 26(2), 2023 |
Number 26
VOL. 26, 2023 Supplement |
Number 26
VOL. 26(1), 2023 |
Number 25
VOL. 25(2), 2022 |
Number 25
VOL. 25 (1), 2022 |
Number 24
VOL. 24(2), 2021 |
Number 24
VOL. 24(1), 2021 |
Number 23
VOL. 23(2), 2020 |
Number 22
VOL. 22(2), 2019 |
Number 22
VOL. 22(1), 2019 |
Number 22
VOL. 22, 2019 Supplement |
Number 21
VOL. 21(2), 2018 |
Number 21
VOL. 21 (1), 2018 |
Number 21
VOL. 21, 2018 Supplement |
Number 20
VOL. 20 (2), 2017 |
Number 20
VOL. 20 (1), 2017 |
Number 19
VOL. 19 (2), 2016 |
Number 19
VOL. 19 (1), 2016 |
Number 18
VOL. 18 (2), 2015 |
Number 18
VOL. 18 (1), 2015 |
Number 17
VOL. 17 (2), 2014 |
Number 17
VOL. 17 (1), 2014 |
Number 16
VOL. 16 (2), 2013 |
Number 16
VOL. 16 (1), 2013 |
Number 15
VOL. 15 (2), 2012 |
Number 15
VOL. 15, 2012 Supplement |
Number 15
Vol. 15 (1), 2012 |
Number 14
14 - Vol. 14 (2), 2011 |
Number 14
The 9th Balkan Congress of Medical Genetics |
Number 14
14 - Vol. 14 (1), 2011 |
Number 13
Vol. 13 (2), 2010 |
Number 13
Vol.13 (1), 2010 |
Number 12
Vol.12 (2), 2009 |
Number 12
Vol.12 (1), 2009 |
Number 11
Vol.11 (2),2008 |
Number 11
Vol.11 (1),2008 |
Number 10
Vol.10 (2), 2007 |
Number 10
10 (1),2007 |
Number 9
1&2, 2006 |
Number 9
3&4, 2006 |
Number 8
1&2, 2005 |
Number 8
3&4, 2004 |
Number 7
1&2, 2004 |
Number 6
3&4, 2003 |
Number 6
1&2, 2003 |
Number 5
3&4, 2002 |
Number 5
1&2, 2002 |
Number 4
Vol.3 (4), 2000 |
Number 4
Vol.2 (4), 1999 |
Number 4
Vol.1 (4), 1998 |
Number 4
3&4, 2001 |
Number 4
1&2, 2001 |
Number 3
Vol.3 (3), 2000 |
Number 3
Vol.2 (3), 1999 |
Number 3
Vol.1 (3), 1998 |
Number 2
Vol.3(2), 2000 |
Number 2
Vol.1 (2), 1998 |
Number 2
Vol.2 (2), 1999 |
Number 1
Vol.3 (1), 2000 |
Number 1
Vol.2 (1), 1999 |
Number 1
Vol.1 (1), 1998 |
|
|
