PROS AND CONS FOR FLUORESCENT IN SITU HYBRIDIZATION, KARYOTYPING AND NEXT GENERATION SEQUENCING FOR DIAGNOSIS AND FOLLOW-UP OF MULTIPLE MYELOMA
Ikbal Atli E, Gurkan H, Onur Kirkizlar H, Atli E, Demir S, Yalcintepe S, Kalkan R, Demir AM
*Corresponding Author: Assistant Professor Emine Ikbal Atli, Department of Medical Genetics, Faculty of Medicine, Trakya University, Balkan Campus, Highway D100, Edirne, Turkey 22030. Tel: +284-235- 76-41/23-30. Fax: +284-235-86-52. E-mail: eikbalatli@trakya.edu.tr
page: 59

REFERENCES

1. Bolli N, Biancon G, Moarii M, Gimondi S, Li Y, de Philippis C, et al. Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups. Leukemia. 2018; 32(12): 2604-2616. 2. Li S, Lim HH, Woo KS, Kim SH, Han JY. A retrospective analysis of cytogenetic alterations in patients with newly diagnosed multiple myeloma: A single center study in Korea. Blood Res. 2016; 51(2): 122-126. 3. Rajkumar SV. Multiple myeloma: 2014 Update on diagnosis, risk-stratification, and management. Am J He-matol. 2014; 89(10): 999-1009. 4. Talley PJ, Chantry AD, Buckle CH. Genetics in myeloma: Genetic technologies and their application to screening approaches in myeloma. Br Med Bull. 2015; 113(1): 15-30. 5. Munshi NC, Anderson KC, Bergsagel PL, Shaughnessy J, Palumbo A, Durie B, et al. Consensus recommendations for risk stratification in multiple myeloma: Report of the International Myeloma Workshop Consensus Panel 2. Blood. 2011; 117(18): 4696-4700. 6. Yellapantula V, Hultcrantz M, Rustad EH, Was-serman E, Londono D, Cimera R, et al. Comprehensive detection of recurring genomic abnormalities: A targeted sequencing approach for multiple myeloma. Blood Cancer J. 2019; 9(12): 101-109. 7. Aydin C, Ulas T, Hangul C, Yucel OK, Iltar U, Salim O, et al. Conventional cytogenetics and interphase fluorescence in situ hybridization results in multiple myeloma: A Turkey laboratory analysis of 381 cases. Indian J Hematol Blood Transfus. 2020; 36(2): 284- 291. doi: 10. 1007/s12288-019-01215-5. Epub 2019 Oct 25. 8. Fonseca R, Barlogie B, Bataille R, Bastard C, Bergsagel PL, Chesi M, et al. Genetics and cytogenetics of multiple myeloma: A workshop report. Cancer Res. 2004; 64(4): 1546-1558. 9. McGowan-Jordan J, Simons A, Schmid M, editors. An International System for Human Cytogenomic Nomenclature (ISCN 2016). Basel, Switzerland: Karger, 2016. 10. Romano A, Palumbo GA, Parrinello NL, Conti-cello C, Martello M, Terragna C. Minimal residual disease assessment within the bone marrow of multiple myeloma: A review of caveats, clinical significance and future perspectives. Front Oncol. 2019; 9(20): 699. 11. Richards S, Aziz N, Bale S, Bick D, Das S, Gastier- Foster J, et al. Standards and guidelines for the interpretation of sequence variants: A joint concensus recommendation of the American College of Medical Genetics and Genomics and the Association of Molecular Pathology. Genet Med. 2015; 17(5): 405-424. doi: 10. 1038/gim. 2015.30. 12. Kapoor P, Fonseca R, Rajkumar SV, Sinha S, Gertz MA, Stewart AK, et al. Evidence for cytogenetic and fluorescence in situ hybridization risk stratification of newly diagnosed multiple myeloma in the era of novel therapies. Mayo Clin Proc. 2010; 85(6): 532-537. 13. Saxe D, Seo EJ, Bergeron MB, Han JY. Recent advances in cytogenetic characterization of multiple myeloma. Int J Lab Hematol. 2019; 41(1): 5-14. 14. Kaufmann H, Ackermann J, Greinix H, Nösslinger T, Gisslinger H, Keck A, et al. Beneficial effect of highdose chemotherapy in multiple myeloma patients with unfavorable prognostic features. Ann Oncol. 2003; 14(11): 1667-1672. 15. Durak BA, Akay OM, Sungar G, Bademci G, Aslan V, Caferler J, et al. Conventional and molecular cytogenetic analyses in Turkish patients with multiple myeloma. Turk J Haematol. 2012; 29(2): 135-142.



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