ASPECTS OF ANCIENT MITOCHONDRIAL
DNA ANALYSIS IN DIFFERENT POPULATIONS
FOR UNDERSTANDING HUMAN EVOLUTION
Nesheva DV
*Corresponding Author: Desislava V. Nesheva, Department of Medical Genetics, Medical Faculty, Medical University,
2 Zdrave str., fl. 6, 1431 Sofia, Bulgaria. Tel.: +35-92-917-2735; E-mail: desislava.nesheva@gmail.com
page: 5
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CONCLUSIONS
In recent years, anthropologists and geneticists
joined to create a map of possible prehistoric human
migration routes and time scales for a detailed reconstruction
of prehistoric and historic events. They
used ancient and modern data and combined the information
to create a picture of our history since the
appearance of modern humans 200,000 years ago in
East Africa.
There are still only small amounts of data for
the genetic makeup of the ancient populations. The
available data are scarce and there is a necessity of
more research in this field in order to fill the gap of
the European map of ancient populations who lived
in this land at different periods of time.
By combining and comparing present and future
results, we can create a map of ancient populations
and their relationships from the first settled groups
to their contemporaries in the present day countries.
The process of creating the full picture of human evolution
is complicated and needs further analyses in
places from which aDNA has not yet been surveyed.
The structure and evolution of the mtDNA gene
pool of contemporary Bulgarians has been previously
analyzed in a large sample comprising 855 individuals
[63]. In order to further clarify and directly observe the gradual changes of the matrilineal composition of
Bulgarians, we will perform phylogenetic analyses of
ancient DNA retrieved from human remains found in
different places of the country and dating to different
periods of the Bulgarian past. The obtained data will
contribute not only to the better understanding of the
Bulgarian genetic past, but it will also shed new light
on the European genetic evolution.
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