PRELIMINARY FINDINGS OF α-ACTININ-3 GENE
DISTRIBUTION IN ELITE TURKISH WIND SURFERS
Ulucan K1, Göle S1, Altindas N2, Güney AI3
*Corresponding Author: Dr. Korkut Ulucan, Department of Molecular Biology and Genetics, Faculty of Engineering
and Natural Sciences, Üsküdar University, Altunizade Mahallesi, Haluk Turksoy Sok., No. 14 Uskudar,
Istanbul 34662, Turkey; +90-216-400-2222-2409, +90-216-474-1256; korkutulucan@hotmail.com
page: 69
|
|
DISCUSSION
Yang et al. [4] initiated the discussion about
ACTN3 influence on elite athletic performance and
was soon followed by others [1,3,6]. To date, several
polymorphism determination studies have been
done by many researchers in order to find the suitable
genotype in different sports. Some of these studies
suggest the RR and RX genotypes as having advantages
in power sports and correlated positively with
strength/power athletes [6-8]. In contrast, Norman et
al. [9] suggested that individuals with the XX genotype
who had no wild-type ACTN3 expression, may
benefit endurance performance due to evolving type
I muscle fibers. Additionally, a shift in the metabolic
path-way, promoting aerobic performance, was reported
in ACTN3 knockout mice [10]. There are also
other studies showing the association between the
ACTN3 XX genotype and endurance athletic capacity
[4,11,12]. In our study group, seven of the surfers had
at least one X allele, five of them were heterozygous and two were homozygous, and these results are in
agreement with the latter studies. On the other hand,
there are some other reports in which the ACTN3
XX genotype is not associated with endurance sports
[13-15]. In our cohort, only one surfer had the RR
genotype, which was in agreement with these studies.
To the best of our knowledge, there are no reports
that examined the ACTN3 polymorphism in surfers
and also in Turkish wind surfers. Sanlısoy et al. [16]
examined the R577X polymorphism in the elite athletes
of the Aegean region in Turkey, and reported
a significant difference between elite athletes and
sedentary individuals.
The main limitation of the study was the low
number of elite Turkish wind surfers. In this report,
we analyzed eight National Team medal winner wind
surfers. This limited number of elite surfers represents
the developing nature of professional wind surfing.
The interest in wind surfing is growing and within a
few years, the number of the individuals competing
in wind surfing events is expected to increase.
In conclusion, the X allele of the ACTN3 plays an
important role in the eight elite Turkish wind surfers.
More-over, it is difficult to predict an individual’s
sporting ability based solely on only one type of polymorphism.
In future, with the improvement in molecular
science and by the addition of related genetic
variations, genetic testing will play more important
roles for deciding the proper type of sports. However,
due to the limited number of examined subjects, we
are unable to comment on the effect of ACTN3 on
Turkish wind surfers. We hope this preliminary finding
will contribute to the literature about the effect
of the ACTN3 gene in surfing and will be supported
by further studies.
|
|
|
|
 |
Number 27
VOL. 27 (2), 2024 |
Number 27
VOL. 27 (1), 2024 |
Number 26
Number 26 VOL. 26(2), 2023 All in one |
Number 26
VOL. 26(2), 2023 |
Number 26
VOL. 26, 2023 Supplement |
Number 26
VOL. 26(1), 2023 |
Number 25
VOL. 25(2), 2022 |
Number 25
VOL. 25 (1), 2022 |
Number 24
VOL. 24(2), 2021 |
Number 24
VOL. 24(1), 2021 |
Number 23
VOL. 23(2), 2020 |
Number 22
VOL. 22(2), 2019 |
Number 22
VOL. 22(1), 2019 |
Number 22
VOL. 22, 2019 Supplement |
Number 21
VOL. 21(2), 2018 |
Number 21
VOL. 21 (1), 2018 |
Number 21
VOL. 21, 2018 Supplement |
Number 20
VOL. 20 (2), 2017 |
Number 20
VOL. 20 (1), 2017 |
Number 19
VOL. 19 (2), 2016 |
Number 19
VOL. 19 (1), 2016 |
Number 18
VOL. 18 (2), 2015 |
Number 18
VOL. 18 (1), 2015 |
Number 17
VOL. 17 (2), 2014 |
Number 17
VOL. 17 (1), 2014 |
Number 16
VOL. 16 (2), 2013 |
Number 16
VOL. 16 (1), 2013 |
Number 15
VOL. 15 (2), 2012 |
Number 15
VOL. 15, 2012 Supplement |
Number 15
Vol. 15 (1), 2012 |
Number 14
14 - Vol. 14 (2), 2011 |
Number 14
The 9th Balkan Congress of Medical Genetics |
Number 14
14 - Vol. 14 (1), 2011 |
Number 13
Vol. 13 (2), 2010 |
Number 13
Vol.13 (1), 2010 |
Number 12
Vol.12 (2), 2009 |
Number 12
Vol.12 (1), 2009 |
Number 11
Vol.11 (2),2008 |
Number 11
Vol.11 (1),2008 |
Number 10
Vol.10 (2), 2007 |
Number 10
10 (1),2007 |
Number 9
1&2, 2006 |
Number 9
3&4, 2006 |
Number 8
1&2, 2005 |
Number 8
3&4, 2004 |
Number 7
1&2, 2004 |
Number 6
3&4, 2003 |
Number 6
1&2, 2003 |
Number 5
3&4, 2002 |
Number 5
1&2, 2002 |
Number 4
Vol.3 (4), 2000 |
Number 4
Vol.2 (4), 1999 |
Number 4
Vol.1 (4), 1998 |
Number 4
3&4, 2001 |
Number 4
1&2, 2001 |
Number 3
Vol.3 (3), 2000 |
Number 3
Vol.2 (3), 1999 |
Number 3
Vol.1 (3), 1998 |
Number 2
Vol.3(2), 2000 |
Number 2
Vol.1 (2), 1998 |
Number 2
Vol.2 (2), 1999 |
Number 1
Vol.3 (1), 2000 |
Number 1
Vol.2 (1), 1999 |
Number 1
Vol.1 (1), 1998 |
|
|
