CHROMOSOMAL POLYMORPHISMS INVOLVED IN
REPRODUCTIVE FAILURE IN THE ROMANIAN POPULATION
Mierla D1,2*, Stoian V2
*Corresponding Author: Dana Mierla MD, Department of Genetics, Faculty of Biology, University of Bucharest,
Bucharest, Romania; Tel.: +40721479083; E-mail: dana_mierla@yahoo.com
page: 23
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CONCLUSIONS
Chromosomal abnormalities and even heteromorphisms
are significant etiological factors leading to
fertility problems. The statistically significantly higher
incidence of heterochromatic variations found in infertile
individuals in this study emphasizes the need to
evaluate their role in infertility and subfertility.
The overall high prevalence of chromosomal
polymor-phisms in infertile couples, compared to
the normal population, needs to be confirmed with
further investigations and larger study populations to
delineate the role of “harmless” chromosomal aberrations
in the etiology of infertility.
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