INFLUENCE OF THE SCN1A IVS5N + 5 G>A
POLYMORPHISM ON THERAPY
WITH CARBAMAZEPINE FOR EPILEPSY
Sterjev Z1,*, Kiteva G2, Cvetkovska E2, Petrov I2, Kuzmanovski I2, Ribarska TJ3,
Nestorovska KA1, Matevska N1,Trajkovik-Jolevska S3, Dimovski AJ1, Suturkova, Lj1
*Corresponding Author: Zoran Sterjev, M. Sei. Pharm Institute of Pharmaceutical Chemistry, Faculty of
Pharmacy, University “St. Cyril and Methodius,” str. Vodnjanska 17, 1000 Skopje, Republic of Macedonia;
Tel./Fax:+38-923-120-229; E-mail: zost@ff.ukim.edu.mk
page: 19
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REFERENCES
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A common polymorphism in the SCN1A gene associates
with phenytoin serum levels at maintenance dose.
Pharmacogenet Genomics. 2006; 16(10): 721-726.
7. Abe T, Seo T, Ishitsu T, Nakagawa T, Hori M,
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a cis-acting polymorphism to infl uence the proportions
of drug-responsive splice variants of SCN1A.
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Oterino A, Valdizán EM, Nicolás JM, Adín J, Armijo
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12. Manna I, Gambardella A, Bianchi A, Striano P,
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Neve A, Michelucci R, Muscas GC, Paravidino R,
Zaccara G, Zucca C, Zara F, Perucca E. A functional
polymorphism in the SCN1A gene does not infl
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