ASSOCIATION OF PLACENTA PREVIA WITH A HISTORY
OF PREVIOUS CESARIAN DELIVERIES AND INDICATIONS
FOR A POSSIBLE ROLE OF A GENETIC COMPONENT
Matalliotakis M1,*, Velegrakis A1, Goulielmos GN2, Niraki E1, Patelarou AE3, Matalliotakis I1
*Corresponding Author: Dr. Michail Matalliotakis, Venizeleio & Pananio General Hospital of Heraklion,
Knossos Avenue, 71409 Heraklion, Greece. Tel: +30-281-036-8304. Mobile: +30-694-386-1582. Fax: +30-281-036-8305.
E-mail: mihalismat@hotmail.com
page: 5
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Abstract
A prior Cesaria section (C-section) is an important
risk factor that leads to endometrial damage and abnormal
implantation of the placenta. Our retrospective study aims
to correlate the frequency of placenta previa to previous
C-sections, to determine the effect of male gender in this
condition and to evaluate further the maternal outcome.
Seventy-six cases with placenta previa were selected out
of 5200 live births. Diagnosis was confirmed by ultrasound
and in the operating theater. In the 76 women examined, we
found 50 cases with a history of a previous C-section (66.0%)
and 49 male offspring (65.0%) (p <0.001), with a mean birth
weight of 2635 ± 740 g. Of all these patients, six (8.0%) cases
developed placenta percreta, seven (9.0%) were transferred
to the intensive care unit (ICU), 14 (18.0%) women needed
blood transfusion and eight (11.0%) underwent hysterectomy.
The results of our series show a strong correlation
of placenta previa to a history of previous C-sections and a
predominance of male fetuses. Early recognition and proper
monitoring could minimize the possibility of a poor outcome.
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